Neurotrophin-3-loaded multichannel nanofibrous scaffolds promoted anti-inflammation, neuronal differentiation, and functional recovery after spinal cord injury

X Sun, C Zhang, J Xu, H Zhai, S Liu, Y Xu… - ACS Biomaterials …, 2020 - ACS Publications
collagen/astrocytic scar formation limited, but the functional … as the guidance for axonal
regeneration and outgrowth, but also … slightly improved microenvironment for nerve regeneration. …

Scaffold mediated delivery of drugs/genes for promoting nerve regeneration via gene silencing/pathway inhibition after traumatic nerve injuries

N Zhang - 2020 - dr.ntu.edu.sg
… topographical cues to enhance nerve regeneration are also … promote significant axon
regeneration and functional recovery. … of drug-loaded conduits in sciatic nerve transected rats and …

A hyaluronic acid/silk fibroin/poly-dopamine-coated biomimetic hydrogel scaffold with incorporated neurotrophin-3 for spinal cord injury repair

Q Sha, Y Wang, Z Zhu, H Wang, H Qiu, W Niu, X Li… - Acta Biomaterialia, 2023 - Elsevier
… Here, we adopted a mussel-inspired strategy to functionalize … to NT-3-mediated tissue
regeneration and the integration of … glial scars and enhanced nerve regeneration and myelination …

[HTML][HTML] Spinal cord conduits for spinal cord injury regeneration

Y Ma, Q Chen, W Li, H Su, S Li, Y Zhu, J Zhou… - … Regeneration, 2023 - Elsevier
… precursor cells to enhance nerve regeneration and angiogenesis. … endogenous nerve
regeneration by bridging the spinal cord with … and degradability of some functional materials (eg, …

[HTML][HTML] Collagen for neural tissue engineering: Materials, strategies, and challenges

WH Huang, SL Ding, XY Zhao, K Li, HT Guo… - Materials Today Bio, 2023 - Elsevier
Multichannel collagen scaffolds as peripheral nerve conduits … of biomaterials in NTE, including
neurotrophin-3 (NT-3), fibroblast … , axonal regeneration is enhanced to achieve functional

[HTML][HTML] Novel innovations in cell and gene therapies for spinal cord injury

MM Zavvarian, A Toossi, M Khazaei, J Hong… - …, 2020 - ncbi.nlm.nih.gov
… -mediated Cre–LoxP system enables axonal regeneration in … studies to improve regeneration
and functional recovery after … into the spinal cord of rats with transection SCIs resulted in …

[HTML][HTML] Construction of a niche-specific spinal white matter-like tissue to promote directional axon regeneration and myelination for rat spinal cord injury repair

BQ Lai, YR Bai, WT Han, B Zhang, S Liu, JH Sun… - Bioactive Materials, 2022 - Elsevier
… tightly bind neurotrophin-3 (NT-3) and promotes axon regeneration by … to increase regeneration
of neuronal axons, failure of … axon regeneration and myelination and facilitate functional

Advances in biomaterial‐based spinal cord injury repair

H Shen, C Fan, Z You, Z Xiao… - Advanced Functional …, 2022 - Wiley Online Library
… promote axon regeneration and facilitate neuronalmultichannel poly(propylene fumarate)
(PPF) scaffold combined with collagen to deliver neurotrophin-3 (NT-3) to promote axonal

Natural polymer‐derived bioscaffolds for peripheral nerve regeneration

H Zhang, J Guo, Y Wang, L Shang… - Advanced Functional …, 2022 - Wiley Online Library
… use of multichannel collagen nerve conduits could control … -derived neurotrophic factor
(BDNF), neurotrophin-3 (NT-3), and … with improved nerve regeneration and functional restoration, …

[HTML][HTML] Fabrication techniques of nerve guidance conduits for nerve regeneration

NU Kang, SJ Lee, SJ Gwak - Yonsei medical journal, 2022 - ncbi.nlm.nih.gov
… The multichannel design is a conduit design with … functional and morphological nerve
regeneration. Conclusion: … factor (BDNF), neurotrophin 3, vascular endothelial growth factor …